Elmi Laboratories

Bone profile blood test

Normal Reference Range

ALP:
0 – 0.5 yrs = 57 – 265U/L
0.5 – 10 yrs = 100 – 360U/L
10 – 17 yrs = 100 – 450U/L
>17 yrs = 25 – 115U/L

Calcium/ Corrected Calcium:
2.2 – 2.6mmol/L

Albumin:
38 – 50 g/L

Phosphate:
0 – 2 Days = 1.4 – 2.8mmol/L
2 Days – 12 yrs = 1.3 – 2.1mmol/L
12 – 20 yrs = 1.1 – 2.0mmol/L
>20 yrs = 0.8 – 1.4mmol/L

Magnesium:
0.7 - 1.0 mmol/L

Test Information

The bone profile also includes the ALP assay, albumin, phosphate, magnesium, and ionisable calcium. The ratio of bound to unbound calcium can be more easily estimated via albumin measurement since inorganic phosphate and calcium concentrations are related to bone formation and resorption. Only unbound (ionised) calcium is accessible for cellular action. For clinical diagnosis and treatment, using corrected calcium levels is advised. Important: Patients with very low albumin levels (20 g/L) should have their ionised calcium levels measured using blood gas analysers rather than serum total calcium readings since a corrected calcium level cannot be calculated using the conventional method based on albumin level. The ALP assay serves as a measure of osteoblastic and osteoclast-mediated bone turnover.

Clinical Indications

Assessment suspected bone disease: Osteoporosis, Parathyroid disorders and osteolytic lesions secondary to metastasis.

Sample Required

5mL serum sample blood tube is required for bone profile blood test

Min. sample volume

0.5mL

Special Instructions and Precautions

Not applicable

Time Limits For Retrospective Testing

2 days

Any factors affecting the test

Not applicable

Turnaround Time

4 hrs

Referral centre (if applicable)

Not applicable

Test Code

BONE

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