Alkaline phosphatase isoenzymes Blood Test
Normal Reference Range
Liver/Biliary Fractions (L1, L2): = Approx.: 60% of Total
Bone Fraction (B): = Approx.: 30% of Total
Bone Fraction (B): = <50U/L
Intestinal Fractions (I1, I2, I3) and Placental Fractions (P1, P2) =
i.e. I1+I2+I3+P1+P2: = <10%*
Note: Placental fractions may be much higher if the subject is pregnant or malignancy present
Test Information
Causes of normal-to-elevated ALP levels include: cholestatis, biliary obstruction, bone disease, healing fractures, hepatitis, hyperparathyroidism, liver disease, osteoblastic bone cancers, osteomalacia, Paget’s disease and Rickets.
Clinical Indications
• Elevated ALP and/or suspected liver/bone pathology
• Assessment of hyperparathyroidism
• Assessement of extent of bone loss to implement vitamin D supplementation in high risk cases eg. bariatric surgery patients
Sample Required
5mL serum sample tube is required for Alkaline phosphatase isoenzymes blood test
Min. sample volume
0.5mL
Special Instructions and Precautions
Not applicable
Time Limits For Retrospective Testing
Not applicable
Any factors affecting the test
Not applicable
Turnaround Time
Up to 4 days
Referral centre (if applicable)
Not applicable
Test Code
APIS